Dr. Edson R. A. Oliveira


Dr. Edson Roberto Alves de Oliveira

Instituto de Química
Universidade Federal do Rio de Janeiro
Av. Athos da Silveira Ramos, 149
Centro de Tecnologia, Bloco A, Sala 609
21941-909, Cidade Universitária
Rio de Janeiro – RJ, Brazil
  +55-21-3938-7132
  +55-21-98226-5037
edsonrao@iq.ufrj.br

Background:

Pharmacist specialized in Biochemistry. M.Sc in Science and PhD in Molecular and Cellular Biology with emphasis in Virology/Immunology. Developed studies in vaccine research against dengue using DNA-immunization approach. Currently, postdoctoral fellow at UFRJ, interested in structural research of viral proteins, immunological aspects of viral infections and regulatory roles in Molecular and Cellular Biology.

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Teaching:

Publications:

2018

Salomão NG; Rabelo K; Póvoa TF; Alves AM; Costa SM; Gonçalves AJ; Amorim JF; Azevedo AS; Nunes PC; Basílio-de-Oliveira C; Basílio-de-Oliveira R; Geraldo LH; Fonseca CG; Lima FR; Mohana-Borges R; Silva EM; Santos FB; Oliveira ER; Paes MV
BALB/c mice infected with DENV-2 strain 66985 by the intravenous route display injury in the central nervous system. Scientific Reports. 2018; 8:9754.

Rabelo K; Oliveira ER; Almeida CJ; Alves AM; Costa SM
Evaluation of different transfection methodologies to achieve efficient expression of the NS1 dengue protein in HepG2 cells. Virus Reviews & Research, 2018; 23:11.

Rabelo K; Souza LJ; Salomão NG; Oliveira ER; Sentinelli LP; Lacerda MS; Saraquino PB; Rosman FC; Basílio-de-Oliveira R; Carvalho JJ; Paes MV
Placental inflammation and fetal injury in a rare Zika case associated to Guillain-Barré syndrome and abortion. Frontiers in Microbiology. 2018; 7:1018.

2017

Oliveira ER; Póvoa TF; Nuovo GJ; Allonso D; Salomão NG; Basílio-de-Oliveira CA; Geraldo LHM; Fonseca CG; Lima FRS; Mohana-Borges R; Paes MV
Dengue fatal cases present virus-specific HMGB1 response in peripheral organs. Scientific Reports. 2017; 7:16011.

Oliveira ER; de Alencastro RB; Horta BA
New insights into flavivirus biology: the influence of pH over interactions between prM and E proteins. Journal of Computer-Aided Molecular Design. 2017; 31:1009-1019.

David KS; Oliveira ER; Horta BA; Valente AP; de Paula VS
Insights into chemokine ligand 2 – chemokine receptor 2 molecular recognition: a step forward towards anti-chemotactic agents. Biochemistry. 2017; 56:3197-3210.

Oliveira ER; Mohana-Borges R; de Alencastro RB; Horta BA
The flavivirus capsid protein: Structure, function and perspectives towards drug design. Virus research. 2017; 227:115-123.

2016

Póvoa TF; Oliveira ER; Basílio-de-Oliveira CA; Nuovo GJ; Chagas VL; Salomão NG; Mota EM; Paes MV
Peripheral organs of dengue fatal cases present strong pro-inflammatory response with participation of IFN-gamma-, TNF-alpha- and RANTES-producing cells. PloS one. 2016; 11:e0168973.

Oliveira ER; Gonçalves AJ; Costa SM; Azevedo AS; Mantuano-Barradas M; Nogueira AC; Alves AM
Aspects of T cell-mediated immunity induced in mice by a DNA vaccine based on the dengue-NS1 antigen after challenge by the intracerebral route. PloS one. 2016; 11:e0163240.

Oliveira ER; de Alencastro RB; Horta BA
The mechanism by which P250L mutation impairs flavivirus-NS1 dimerization: an investigation based on molecular dynamics simulations. Eur Biophys J. 2016; 45:573-80.

Oliveira ER; Amorim JF; Paes MV; Azevedo AS; Gonçalves AJ; Costa SM; Mantuano-Barradas M; Póvoa TF; de Meis J; Basílio-de-Oliveira CA; Nogueira AC; Alves AM
Peripheral effects induced in BALB/c mice infected with DENV by the intracerebral route. Virology. 2016; 489:95-107.

2015

Gonçalves AJ; Oliveira ER; Costa SM; Paes MV; Silva JF; Azevedo AS; Mantuano-Barradas M; Nogueira AC; Almeida CJ; Alves AM
Cooperation between CD4+ T cells and humoral immunity Is critical for protection against dengue using a DNA vaccine based on the NS1 antigen. PLoS Negl Trop Dis. 2015; 9:e0004277.

2013

de Oliveira ER; Lima BM; de Moura WC; Nogueira AC
Reduction of cell viability induced by IFN-alpha generates impaired data on antiviral assay using Hep-2C cells. J Immunol Methods. 2013; 400-401:97-105.

2012

de Oliveira ER; Lima BM; dos Santos BA; de Moura WC; Nogueira AC
Potency determination of recombinant IFN-alpha based on phosphorylated STAT1 using flow cytometry. J Immunol Methods. 2012; 375:271-275.